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图书简介

　　“以器官系统为中心”的医学教学模式是国际医学教育的趋势。本系列书是世界著名医药卫生出版集团爱思唯尔公司出版的一套“以器官系统为中心”的医学基础课程教材。该套教材第1版出版后受到世界各地许多医学院校的欢迎，并被多家进行“以器官系统为中心”教学的医学院校选定为教材。第2版根据第1版出版后教师和学生的反馈意见，结合医学知识的更新进行了全新修订。在编写内容上，该系列教材强调基础与临床的整合。每一章节都是围绕着一个临床病例展开，通过对病人问题的呈现以及解决过程引出对相关知识的探究，从而使与器官系统结构、功能以及疾病相关的重要的基础医学知识得到了完善的整合。在版式安排上，图框中的病例资料与正文中的医学知识完美匹配，一步一步地激起读者的求知欲望。本册为《泌尿系统》。

目录

1 URINARY TRACT STRUCTURE AND INFECTION
  Introduction
  Normal anatomy of the urinary tract
  Structure of the kidney
  Innervation of the urinary tract
  Embryology of the kidney and urinary tract
  Infection of the urinary tract
  Aetiology and pathogenesis of urinary tract
  infection
  Investigation of urinary tract infection
  Imaging of the urinary tract
  Vesicoureteric reflux
  Overview: treatment of urinary tract infections
2 BODY FLUIDS, NEPHRON FUNCTION AND DIURETICS
  Introduction
  Body fluid and electrolyte distribution
  Functional anatomy of the nephron
  Sodium transport
  Regulation of sodium transport
  Potassium transport
  Pharmacology of diuretic agents
  Principles of fluid and electrolyte replacement
  therapy
3 WATER BALANCE AND REGULATION OF OSMOLALITY
  Introduction
  Causes and assessment of polyuria
  Renal mechanisms for urine concentration
  Feedback control of plasma osmolality
  Failure to concentrate the urine
  Failure to dilute the urine
4 ACID-BASE BALANCE AND REGULATION OF pH
  Introduction
  Role of the kidney in H+ balance
  Disturbances of acid-base balance: acidosis
  Disturbances of acid-base balance: alkalosis
  Summary of findings in principal acid-base
  disturbances
5 GLOMERULAR FILTRATION AND ACUTE KIDNEY INJURY
  Introduction
  Renal blood flow
  Glomerular filtration
  Autoregulation of renal blood flow and glomerular
  filtration rate
  Renal excretion and the clearance formula
  Measuring the glomerular filtration rate
  Urea
  Pathophysiology of oliguria
  Causes of acute kidney injury
  Acute tubular necrosis
  Overview: assessment and management of a
  patient with acute kidney injury
  Biochemical changes in acute kidney injury
  Complications of acute kidney injury
  Management of acute kidney injury
6 PROTEINURIA AND THE NEPHROTIC SYNDROME
  Introduction
  Pathophysiology of oedema formation
  Glomerular anatomy and the filtration barrier
  Normal and abnormal proteinuria
  Nephrotic syndrome
  Natural history and response to treatment
7 GLOMERULONEPHRITIS AND THE ACUTE NEPHRITIC SYNDROME
  Introduction
  Urinary sediment examination
  Presentation and consequences of glomerular
  disease
  Investigation of glomerulonephritis
  Differential diagnosis of acute
  glomerulonephritis
  Pathogenesis of acute glomerulonephritis
  Outcome of glomerulonephritis
  Clinicopathological correlations in
  glomerulonephritis
8 DIABETIC NEPHROPATHY AND CHRONIC KIDNEY DISEASE
  Introduction
  Presentation of chronic kidney disease
  Stages of chronic kidney disease
  Causes of chronic kidney disease _
  Pathology of diabetic nephropathy and chronic
  kidney disease
  Main consequences of chronic kidney disease
  Progression of chronic kidney disease
  Principles of treatment
9 END-STAGE KIDNEY DISEASE AND REPLACEMENT OF RENAL FUNCTION
  Introduction
  Replacement of kidney function
  Principles and modes of dialysis
  Principles and modes of transplantation
  Conservative therapy for advanced chronic kidney
  disease
10 HYPERTENSION AND THE KIDNEY
  Introduction
  Determinants of normal blood pressure and role
  of the kidney
  Pathogenesis of essential hypertension
  The pathology of hypertension
  Principles in the management of hypertension
  Secondary hypertension
11 PREGNANCY AND THE KIDNEY
  Introduction
  Structural changes in the urinary tract during
  pregnancy
  Urinary tract infection in pregnancy
  Renal physiology changes in pregnancy
  Blood pressure and pregnancy
  Hypertension in pregnancy
  Management of hypertension in pregnancy
  Follow-up of patients with hypertension in
  pregnancy
  Pregnancy in patients with pre-existing
  kidney disease
12 URINARY TRACT OBSTRUCTION AND STONES
  Introduction
  Differential diagnosis of loin pain and haematuria
  Imaging of the urinary tract
  Pathophysiology of urinary tract obstruction
  Renal calculi
  Principles of treatment
13  RENAL MASSES AND URINARY TRACT TUMOURS
  Introduction
  Differential diagnosis of a renal mass
  Renal cell carcinoma
  Differential diagnosis of microscopic haematuria
  Transitional cell carcinoma of the bladder
  Other urinary tract tumours
14 DRUGS AND THE KIDNEY
  Introduction
  PART A
  Effect of renal impairment on drug excretion
  Altered pharmacokinetics in renal disease
  Drug dosing in renal failure
  PART B
  Renal impairment induced by drugs
  Renal actions of non-steroidal anti-inflammatory
  drugs
  Mechanisms of nephrotoxicity
  Important causes of nephrotoxicity
Appendix: normal ranges
Glossary
Index

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