图书简介

　　 “以器官系统为中心”的医学教学模式是国际医学教育的趋势。本系列书是世界著名医药卫生出版集团爱思唯尔公司出版的一套“以器官系统为中心”的医学基础课程教材。该套教材第1版出版后受到世界各地许多医学院校的欢迎，并被多家进行“以器官系统为中心”教学的医学院校选定为教材。第2版根据第1版出版后教师和学生的反馈意见，结合医学知识的更新进行了全新修订。在编写内容上，该系列教材强调基础与临床的整合。每一章节都是围绕着一个临床病例展开，通过对病人问题的呈现以及解决过程引出对相关知识的探究，从而使与器官系统结构、功能以及疾病相关的重要的基础医学知识得到了完善的整合。在版式安排上，图框中的病例资料与正文中的医学知识完美匹配，一步一步地激起读者的求知欲望。本册为《呼吸系统》。

目录

1　INTRODUCTION
  Introduction
  What is respiration?
  The need for respiration
  Diffusion in respiration and the circulation
  Timing in the circulation and respiration
  Basic science of respiration
  Drugs
2  STRUCTURE OF THE RESPIRATORY SYSTEM,RELATED TO FUNCTION
  Introduction
  The upper airways
  The intrathoracic airways
  Blood vessels
  Pulmonary hypertension
  The lymphatics
  The nerves
  Gross structure of the respiratory system
  Pleurisy
  The diaphragm and chest wall
  How breathing is brought about
  Embryology
  Air-conditioning
  Metabolic activity
  Metabolism of circulating biologically active substances
  Non-respiratory functions
3  ELASTIC PROPERTIES OF THE RESPIRATORY SYSTEM
  Introduction
  Intrapleural pressure (Ppl)
  Static lung compliance (CL)
  The effect of disease
  The physical basis of lung compliance
4  AIRFLOW IN THE RESPIRATORY SYSTEM
  Introduction
  How airflow is brought about
  The nature of airflow
  The major determinant of flow - radius
  Airways resistance and obstructive pulmonary disease
  The clinical situation
  Sites of airways resistance
  Asthma and airways smooth muscle
  Bronchomotor tone
  Pharmacological treatment of asthma
  Clinical definitions
  Bronchitis and mucus
  Emphysema and radial traction
  Intrapleural pressure and cough
  Clinical tests for changes in resistance
  Work of breathing
5  VENTILATION OF THE RESPIRATORY SYSTEM: THE IMPORTANCE OF ITS LACK OF UNIFORMITY IN DISEASE
  Introduction
  Spirometric abnormalities in disease
  Uneven distribution
  Dead space.
  Alveolar dead space in disease
  The Bohr equation
  Factors affecting physiological dead space
  Alveolar ventilation and respiratory exchange
  The alveolar gas equation
  Distribution of inspired gas
  Other factors influencing distribution
6  GAS EXCHANGE BETWEEN AIR AND BLOOD:DIFFUSION
  The path from air to tissue
  Lung disease and diffusion
  Fick's Law of Diffusion
  Measuring transfer factor
  Treating diffusion difficulties
  Carbon dioxide and other gases
7  THE PULMONARY CIRCULATION: BRINGING BLOOD AND GAS TOGETHER
  The functions of the pulmonary circulation
  The anatomy of the pulmonary circulation
  Matching ventilation and perfusion
  Distribution of blood flow through the lungs
  Regional differences in ventilation in the lungs
  Ventilation/perfusion matching and its effect on blood
  O and CO content
  Shunt
8  CARRIAGE OF GASES BY THE BLOOD AND ACID/BASE BALANCE
  Introduction
  Oxygen transport
  Dissolved oxygen: do we really need Hb and why
  keep it in red cells?
  Carbon dioxide transport
  Acid-base balance
9  CHEMICAL CONTROL OF BREATHING
  Introduction
  Oxygen lack
  Carbon dioxide excess
10　NERVOUS CONTROL OF BREATHING
  Introduction
  The rhythm generator
  Pattern of breathing in COPD
  The respiratory 'centres'
  The medullary groups
  Conscious control of breathing
  Respiratory muscle innervation
  Neuromuscular disorders
  Vagal reflexes
  Dyspnoea
  Other reflexes
11  LUNG FUNCTION TESTS: MEASURING DISABILITY
  Introduction
  Spirometry
  Flow measurements
  Plethysmography
  Lung mechanics
  Transfer factor (diffusing capacity)
  Blood gases
  Gas washouts
  Exercise testing
  Challenge tests
Appendix: some basic science
Glossary
Index

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